Of all the threats to free scientific enquiry, there is one that is perhaps not put on the foreground as much as it should be: the pressure of scientific findings to have immediate, practical applications. In the current climate of chronic funding shortages and anti-scientific sentiments that flourish in both society and politics, it is a problem that is overtaken by more urgent concerns. But just as the delay in developing new antibiotics due to the costs of R&D will cause severe problems in the long term, so this intellectual straitjacket will have long-term consequences that are not immediately apparent. This slim volume shows these concerns are far from new. In fact, they were at the roots of the founding of a remarkable institute.