RNA

Book review – Kin: How We Came to Know Our Microbe Relatives

The problem with many history books is that they are written long after the facts, sometimes when the original protagonists are no longer alive. Historians or journalists often have no choice but to puzzle together the pieces of their story from eyewitness testimony or archival sources. Kin: How We Came to Know Our Microbe Relatives is a welcome exception to this rule. Written by emeritus microbiology professor John L. Ingraham, currently 94 years young, this book gives an intellectual history of the discipline of microbiology based on over seven decades of first-hand involvement and observation.

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Book review – Extended Heredity: A New Understanding of Inheritance and Evolution

In my recent review of She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity, I mentioned how the concept of heredity has become ever fuzzier the more we have learnt about how traits can be passed to the next generation. We have come from a very gene-centric period in biology, but biologists Russell Bonduriansky and Troy Day are ready to shake up the field. Neither a Lamarckian redux nor an attempt to downplay the importance of genes, this book successfully argues that the time has come to take into account non-genetic forms of heredity. Along the way, they provide a very interesting history lesson on how we got here in the first place.

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Book review – The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance

After the recently published Lamarck’s Revenge: How Epigenetics Is Revolutionizing Our Understanding of Evolution’s Past and Present left me little the wiser on how epigenetics actually works, I decided to track down a copy of Nessa Carey’s The Epigenetics Revolution. As one of two popular books published around the same time, it seemed like a good place to start. Peter Ward was right about one thing, this is indeed a landmark book, even if it is now a few years old.

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Book review – Lamarck’s Revenge: How Epigenetics Is Revolutionizing Our Understanding of Evolution’s Past and Present

As one of several intellectuals who wrote about evolution before Darwin, time has not been kind to the French naturalist Jean-Baptiste Lamarck (1744-1829). Reviled during his lifetime by the influential Cuvier, after his death he became best remembered, and ultimately ridiculed, for the idea that characters acquired during an organism’s lifetime are passed on to its offspring. With the rise of the modern field of epigenetics, some of his ideas are making a comeback, albeit modified and adapted for the 21st Century. Palaeontologist and astrobiologist Peter Ward would even like to go so far as to restore some honour to his name and consider epigenetics a neo-Lamarckian process.

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Book review – Microbes from Hell

I recently read about the American microbiologist Carl Woese (1928-2012) and his discovery of a completely new group of single-celled organisms, the Archaea, in Quammen’s book The Tangled Tree: A Radical New History of Life. These mysterious microbes thrive under extreme environmental conditions, so I was intrigued and keen to find out more. The French microbiologist Patrick Forterre here describes these microbes, the research that led to their discovery, and the questions and answers this has thrown up. Originally published in French in 2008 as Microbes de l’Enfer, The University of Chicago Press has now made this book available in English to a wider audience.

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Book review – Gene Machine: The Race to Decipher the Secrets of the Ribosome

DNA has lodged itself in the public imagination as the “blueprint” of life and as other, often slightly deceiving, metaphors. But what happens next? How do organisms actually get anything done with the information coded in DNA? For biologists, this is standard textbook fare: DNA is copied into single-stranded RNA which is then translated, three letters at a time, into amino acids that, when strung together, make up the workhorses of the cell: proteins. The cell organ, or organelle, that does the latter part is the ribosome, which Venki Ramakrishnan introduces here in Gene Machine. He has written a riveting first-hand account of the academic race to describe its structure, and how, in the process, he bagged a shared Nobel Prize in Chemistry in 2009.

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Book review – The Tangled Tree: A Radical New History of Life

After I recently finished Carl Zimmer’s new book She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity, I noticed there was one mechanism of heredity he mentioned only ever so briefly: horizontal gene transfer. Since it does not play a large role in humans, it is understandable he left it aside. And doing it justice would have required almost another book. Luckily, science writer David Quammen is here to give us that book.

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Book review – She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity

If Charles Darwin were to walk into my office today and ask me: “So, what did I miss?” I think I would sit the good man down with a copy of She Has Her Mother’s Laugh, telling him: “Here, this should get you up to speed”. Darwin struggled to explain how traits were being inherited from generation to generation. As New York Times columnist Carl Zimmer shows in this wide-ranging book, the story of heredity has turned out to be both diverse and wonderful, but has also been misappropriated to prop up some horrible ideologies.

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Book review – Viruses: Agents of Evolutionary Invention

When I reviewed Planet of Microbes: The Perils and Potential of Earth’s Essential Life Forms, I remarked that microbes are everywhere. If you are willing to stretch the definition of life a bit further still, there is one entity that is even more numerous and omnipresent: the humble virus. We tend to think of viruses almost exclusively in the context of disease (see for example The Invisible Enemy: A Natural History of Viruses). But, as virologist and pharmaceutical researcher Michael Cordingley shows here, they are so much more than mere pathogens and have a huge influence on evolutionary processes in all organisms. This book paints a remarkable portrait of these unusual life forms.

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Book review – Planet of Microbes: The Perils and Potential of Earth’s Essential Life Forms

What unites deep subterranean caves, hydrothermal vents in the deep sea, our guts, cloud formation, geochemical processes, and astrobiology (the search for life beyond our planet) to name but a few things? Microbes. The tiny, single-celled organisms that we cannot see with the naked eye are everywhere. With Planet of Microbes, Ted Anton makes the point that this world is really theirs, and takes the reader on a tour of the rapid increase in our understanding of their importance, focusing on three major subjects.

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